Job Details

  • Title: Research Associate
  • Code: RCI-47888-1
  • Location: Seattle, WA 98109
  • Posted Date: 05/20/2022
  • Duration: 12 Months
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  Job Description

On-site Role

 

We are seeking an enthusiastic, self-driven individual to join the Gene Delivery Process and Analytical Development team. Our team develops process and technology underpinning critical raw materials used in the manufacturing of engineered T cells, including viral vector.

  • The primary focus of this Research Associate position will be to support upstream and downstream operations in our 50 L pilot lab for production of AAV vectors used for gene delivery and gene editing of our cell therapy products.
  • This team member will support current programs, advance process development of scalable, manufacturing-friendly viral vector processes, and provide non GMP grade viral vector for pre-IND studies. Join us and be part of a team that values collaboration, personal development, and diversity in pursuit of an inclusive and motivating work environment.

Responsibilities:

  • Hands-on experience in upstream (cell culture and transfection conditions) and downstream (clarification, tangential flow filtration, chromatography) unit operations for viral vector production
  • Prepare buffers and process solutions for pilot scale productions
  • Contribute to planning and design of experiments, execution and independent analysis of data.
  • Maintain proper documentation of process data.

Basic Qualifications:

  • M.S. or B.S. in Chemical Engineering, Bioengineering, Biochemistry, Molecular Biology, Virology, or related disciplines
  • 0-2 years of industry experience in process development or related work
  • Independently motivated with the ability to multitask and work in teams
  • Ability to communicate clearly and concisely through oral presentation and technical writing

Preferred Qualifications:

  • Demonstrated ability to read and understand scientific literature
  • Experience in mammalian cell culture and aseptic techniques
  • Experience with downstream equipment and techniques (Chromatography/AKTA, UF/DF, Sterile Filtration)
  • Familiar with statistical analysis and experimental design
  • Familiar with general analytical assays, such as HPLC and ELISA.
  • Additional Job Requirements:
  • Position Handles Hazardous Materials

Additional Job Requirements:  

  • Position Handles Hazardous Materials